| Autor: |
Septia Andini, Joshita Djajadisastra, Mahdi Jufri |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Jurnal Kefarmasian Indonesia, Vol 6, Iss 2, Pp 129-136 (2017) |
| ISSN: |
2354-8770 |
| Popis: |
Kojyl 3 APPA is a compound used for skin lightening. Kojyl 3 APPA has a good solubility in water. This causes the hydrophilic nature kojyl 3 APPA difficult to penetrate through the skin. Transfersom is a carrier system that can improve the effectiveness of drug penetration. This study aims to formulate, characterize and evaluate transfersom preparations containing kojyl 3 APPA. Further more transfersom formulated in a gel formulation. Preparation gel was tested its physical stability and in vitro penetration test against non transfersom kojyl 3 APPA. Transfersom gel formulation is physically proven stable at room temperature, low temperature and high temperature storage. In vitro penetration tests showed that kojyl 3 APPA penetration loaded in transfersom gel was 11,16% while for non transfersom gel 8,02%. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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