Common Carotid Intima-Media Thickness Predicts Occurrence of Carotid Atherosclerotic Plaques

Autor: Dominique Courbon, Pierre-Jean Touboul, Pierre Ducimetière, Mahmoud Zureik, Christine Magne, Claire Bonithon-Kopp, Claudine Berr
Rok vydání: 2000
Předmět:
Zdroj: Arteriosclerosis, Thrombosis, and Vascular Biology. 20:1622-1629
ISSN: 1524-4636
1079-5642
DOI: 10.1161/01.atv.20.6.1622
Popis: Abstract —The role of the increase in the common carotid artery (CCA) intima-media wall thickness (IMT) in the atherosclerotic process is questionable. This longitudinal study examined the predictive value of CCA-IMT measured at baseline examination (at sites free of plaques) on the occurrence of atherosclerotic plaques in the extracranial carotid arteries during 4 years of follow-up study in a sample of 1010 subjects aged 59 to 71 years. Ultrasound examinations were performed at baseline and 2 years and 4 years later. The occurrence of carotid plaques during follow-up was defined as the appearance of ≥1 plaque in previously normal carotid segments and/or the appearance of new plaques in the carotid segments that previously had plaques. Carotid plaque occurrence was observed in 185 subjects (18.3%). Age- and sex- adjusted odds ratios of carotid plaque occurrence were 2.66 (95% CI 1.58 to 4.46, P P
Databáze: OpenAIRE