Fasting serum insulin in relation to fat distribution, serum lipid profile, and blood pressure in European women: the European fat distribution study
| Autor: | J.G.A.J. Hautvast, Giuseppe DiBiase, Massimo Cigolini, Per Björntorp, Jacob C. Seidell, Jadwiga Charzewska, Britt-Marie Ellsinger, L.A. Scuro, Franco Contaldo, V. Szostak |
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| Přispěvatelé: | Youth and Lifestyle |
| Jazyk: | angličtina |
| Rok vydání: | 1991 |
| Předmět: |
Adult
medicine.medical_specialty Waist Endocrinology Diabetes and Metabolism medicine.medical_treatment Physical Exertion Blood Pressure Research Support Body Mass Index chemistry.chemical_compound Endocrinology SDG 3 - Good Health and Well-being Internal medicine medicine Journal Article Humans Insulin Life Science Non-U.S. Gov't Human Nutrition & Health medicine.diagnostic_test Anthropometry business.industry Cholesterol Research Support Non-U.S. Gov't Humane Voeding & Gezondheid Smoking nutritional and metabolic diseases Fasting Circumference Lipids Blood pressure chemistry Adipose Tissue Female Lipid profile business Body mass index |
| Zdroj: | Metabolism : Clinical and Experimental 40 (1991) Metabolism, Clinical and Experimental, 40(8), 781-7. W.B. Saunders Ltd Metabolism : Clinical and Experimental, 40, 781-787 Cigolini, M, Seidell, J C, Charzewska, J, Ellsinger, B M, Dibiase, G, Björntorp, P, Hautvast, J G A J, Contaldo, F, Szostak, V & Scuro, L A 1991, ' Fasting serum insulin in relation to fat distribution, serum lipid profile, and blood pressure in European women : the European Fat Distribution Study ', Metabolism, Clinical and Experimental, vol. 40, no. 8, pp. 781-7 . https://doi.org/10.1016/0026-0495(91)90003-F |
| ISSN: | 0026-0495 |
| Popis: | Samples of 38-year-old women were randomly selected from five European centers: Ede (The Netherlands), Warsaw (Poland), Gothenburg (Sweden), Verona (northern Italy), and Afragola (Naples-southern Italy). In total, 452 healthy women were studied. Anthropometric measurements were taken by one operator in each country after common training of all operators and blood parameters of all women were determined in one laboratory. Body mass index (BMI) was different among centers, mainly due to the higher values in southern Italy. Women from southern Europe had more central fat distribution than women from north European centers. Fasting serum insulin was higher in women from Poland and The Netherlands than in the other three centers. After adjustment for BMI, fasting insulin was significantly related to subscapular skinfold, subscapular to triceps skinfold ratio, waist circumference, and waist to thigh circumference ratio, although the partial correlations varied somewhat between the centers. In the pooled data, waist circumference showed the highest correlations with fasting serum insulin when adjusted for BMI. Fasting serum insulin showed significant partial correlations, adjusted for BMI, with lipid profile and blood pressure only in women from the two Italian centers. In the pooled data, fasting serum insulin was significantly positively correlated with serum triglycerides and total cholesterol and negatively to high-density lipoprotein (HDL) cholesterol and HDL/total cholesterol, independently of BMI and waist circumference. While blood pressure was not related to insulin in the pooled women, when adjusted for BMI and waist circumference; here as well, there were some differences in relationships between the centers.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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