Clinical Practice Guidelines for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia in Adults
| Autor: | George G. Zhanel, Ronald F. Grossman, Sheldon Magder, R Bruce Light, Karl Weiss, Barrie McTaggart, Abraham Born, Gerald A Evans, Coleman Rotstein |
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| Přispěvatelé: | University of Manitoba |
| Rok vydání: | 2008 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty business.industry Mortality rate Ventilator-associated pneumonia Infectious and parasitic diseases RC109-216 medicine.disease Hospital-acquired pneumonia Microbiology Intensive care unit QR1-502 respiratory tract diseases law.invention Clinical Practice Pneumonia Infectious Diseases stomatognathic system law Health care Epidemiology medicine Intensive care medicine business |
| Zdroj: | Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 19, Iss 1, Pp 19-53 (2008) |
| ISSN: | 1712-9532 |
| Popis: | Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are important causes of morbidity and mortality, with mortality rates approaching 62%. HAP and VAP are the second most common cause of nosocomial infection overall, but are the most common cause documented in the intensive care unit setting. In addition, HAP and VAP produce the highest mortality associated with nosocomial infection. As a result, evidence-based guidelines were prepared detailing the epidemiology, microbial etiology, risk factors and clinical manifestations of HAP and VAP. Furthermore, an approach based on the available data, expert opinion and current practice for the provision of care within the Canadian health care system was used to determine risk stratification schemas to enable appropriate diagnosis, antimicrobial management and nonantimicrobial management of HAP and VAP. Finally, prevention and risk-reduction strategies to reduce the risk of acquiring these infections were collated. Future initiatives to enhance more rapid diagnosis and to effect better treatment for resistant pathogens are necessary to reduce morbidity and improve survival. |
| Databáze: | OpenAIRE |
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