Effect of postoperative radiotherapy on the development of small bowel obstruction in patients undergoing staging laparotomy for Hodgkinʼs disease
| Autor: | Peter H. Wiernik, Donald D. Coker, John J. Coleman, Don M. Morris, Robert G. Slawson |
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| Rok vydání: | 1985 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Time Factors Adolescent medicine.medical_treatment Splenectomy Tissue Adhesions Iliac Artery symbols.namesake Postoperative Complications Laparotomy Abdomen medicine Humans Surgical Wound Infection Child Aorta Fisher's exact test Aged Neoplasm Staging Retrospective Studies Radiotherapy business.industry Medical record Pneumonia Middle Aged medicine.disease Hodgkin Disease Surgery Bowel obstruction Radiation therapy medicine.anatomical_structure Oncology symbols Female business Intestinal Obstruction |
| Zdroj: | American Journal of Clinical Oncology. 8:463-467 |
| ISSN: | 0277-3732 |
| DOI: | 10.1097/00000421-198512000-00003 |
| Popis: | Two hundred and ten previously untreated patients with hodgkin's disease underwent staging laparotomy at one institution. Medical records of these patients were retrospectively reviewed. The incidence of small bowel obstruction (SBO); whether or not the patient received abdominal radiotherapy and the portals used; whether or not the patient had undergone a previous operation for unrelated disease; and the outcome of operative treatment for the SBO were noted. Mean follow-up for all patients was 62.6 months (1 to 125 months). Ninety-two patients (Group I) were treated without radiotherapy; two developed SBO (2.2%). Patients treated with abdominal radiotherapy numbered 118 (Group II); seven developed SBO (5.9%). The difference between Groups I and II is not significant. Eighty-two received only paraaortic radiotherapy; two (2.4%) developed SBO. Thirty-six patients underwent combined paraaortic and bilateral iliac radiotherapy (Group IV); five developed SBO (13.9%). Data for Groups III and IV approach statistical significance (p = 0.053; Fisher Exact Test [two-Tail]). All obstructions were secondary to adhesions. Four patients in Group IV had significant morbidity associated with operative treatment of SBO. This was an infection in each case. Infections developed in these patients even when the bowel was not entered. Pneumonia and wound infections were most common. Careful evaluation postoperatively for signs of infection and aggressive pulmonary toilet are recommended. |
| Databáze: | OpenAIRE |
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