Major depressive disorder with anger attacks and cardiovascular risk factors

Autor: Renerio Fraguas, Bettina Bankier, Nicoletta Clementi-Craven, Roy H. Perlis, Jonathan E. Alpert, Maurizio Fava, Dan V. Iosifescu
Rok vydání: 2007
Předmět:
Adult
Male
medicine.medical_specialty
Adolescent
Cross-sectional study
media_common.quotation_subject
Hypercholesterolemia
Hostility
Comorbidity
Anger
Irritability
behavioral disciplines and activities
03 medical and health sciences
0302 clinical medicine
Risk Factors
Internal medicine
Surveys and Questionnaires
mental disorders
medicine
Ambulatory Care
Diabetes Mellitus
Humans
030212 general & internal medicine
Risk factor
Psychiatry
Depression (differential diagnoses)
media_common
Aged
Psychiatric Status Rating Scales
Depressive Disorder
Major

Smoking
Odds ratio
Middle Aged
medicine.disease
030227 psychiatry
Diagnostic and Statistical Manual of Mental Disorders
Psychiatry and Mental health
Cross-Sectional Studies
Logistic Models
Cardiovascular Diseases
Hyperglycemia
Major depressive disorder
Female
medicine.symptom
Psychology
Zdroj: International journal of psychiatry in medicine. 37(1)
ISSN: 0091-2174
Popis: Objective: Depression and anger have been separately associated with cardiovascular risk factors. We investigated if major depressive disorder (MDD) with concomitant anger attacks was associated with cardiovascular risk factors. Method: We measured total serum cholesterol, glycemia, resting blood pressure, and smoking parameters in 333 (52.9% women) MDD non-psychotic outpatients, mean age of 39.4 years. MDD was diagnosed with the Structured Clinical Interview (SC1D) in accordance with the Diagnostic and Statistic Manual of Mental Disorders, Third Edition, Revised (DSM-III-R). The presence of anger attacks was established with the Massachusetts General Hospital Anger Attacks Questionnaire. Results: In a logistic regression analysis, anger attacks were independently associated with cholesterol levels ≥ 200mg/dL (odds ratio [OR], 2.16; 95% confidence interval [CI], 1.18–3.94) and years of smoking >11 (OR, 2.59; 95%CI, 1.32–5.04). Conclusions: MDD with anger attacks was significantly associated with increased cholesterol levels and years of smoking.
Databáze: OpenAIRE