A Review of the Relationship Between Parenteral Nutrition and Metabolic Bone Disease
| Autor: | Matthew J. Geraci, Marcus Ferrone |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Parenteral Nutrition
medicine.medical_specialty Bone density 030309 nutrition & dietetics Medicine (miscellaneous) Disease Bioinformatics Bone and Bones Bone resorption Phosphorus metabolism Metabolic bone disease Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Humans Medicine 0303 health sciences Nutrition and Dietetics business.industry Phosphorus medicine.disease Bone Diseases Metabolic Malnutrition Endocrinology Parenteral nutrition Calcium 030211 gastroenterology & hepatology Complication business |
| Zdroj: | Nutrition in Clinical Practice. 22:329-339 |
| ISSN: | 1941-2452 0884-5336 |
| Popis: | Metabolic bone disease (MBD) refers to the conditions that produce a diffuse decrease in bone density and strength because of an imbalance between bone resorption and bone formation. MBD can be a potential complication in patients receiving chronic parenteral nutrition (PN) therapy and the management of this condition presents a challenge for many clinicians. The etiology of PN-associated MBD is poorly understood, but traditional risk factors can include malnutrition, vitamin and mineral deficiencies, toxic contaminants in the PN solution, concomitant medications, and presence of certain disease states. Although additional studies are warranted to further elucidate the development and management of this condition, the following review discusses some of the important factors that may play a role in the genesis of PN-associated MBD and evaluates some potential strategies for the diagnosis and treatment of this complication. |
| Databáze: | OpenAIRE |
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