Synthesis of some triazolyl-antipyrine derivatives and investigation of analgesic activity

Autor:	Fatma Sultan Kilic, Meltem Sivaci, Guelhan Turan‐Zitouni, Kevser Erol
Přispěvatelé:	Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Anabilim Dalı, Turan, Gülhan
Rok vydání:	2001
Předmět:	Pharmacology Analgesics medicine.drug_class Chemistry Organic Chemistry Analgesic Pain Carboxamide General Medicine Triazoles Chemical synthesis Mice Drug Discovery medicine Triazole derivatives Animals Organic chemistry Analgesic Activity Antipyrine Pain Measurement
Zdroj:	European Journal of Medicinal Chemistry. 36:685-689
ISSN:	0223-5234
DOI:	10.1016/s0223-5234(01)01252-1
Popis:	WOS: 000172327000009 PubMed ID: 11600237 The synthesis of some triazolyl-antipyrine derivatives starting from 4-chloroacetamidoantipyrine and 3-(aryloxyalkyl)-4-ethyl/phenyl-5-mercapto-1,2,4-triazoles is described. The chemical structures of the compounds were elucidated by IR, H-1-NMR and mass spectral studies. These compounds were tested for analgesic activity
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2a913fa95eb4090fcfdb5c7620772c https://doi.org/10.1016/s0223-5234(01)01252-1 Zobrazit plný text záznamu Full Text from ScienceDirect