Expression of pituitary adenylate cyclase-activating polypeptide 1 and 2 receptor mRNA in gallbladder tissue of patients with gallstone or gallbladder polyps
Autor: | Jun-Zhe Jin, Zhong Tian, Jing Kong, Yang Su, Hong Gao, Shuo-Dong Wu, Gang Shi, Zhen-Hai Zhang |
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Jazyk: | angličtina |
Rok vydání: | 2006 |
Předmět: |
Adult
Male medicine.medical_specialty Receptors Vasoactive Intestinal Polypeptide Type I medicine.medical_treatment Adenylate kinase Gallbladder Diseases Gallstones Gallbladder Stone Biology Liver transplantation Gastroenterology Polyps Internal medicine Receptor mrna Gallbladder polyp medicine Humans heterocyclic compounds RNA Messenger Messenger RNA Reverse Transcriptase Polymerase Chain Reaction Gallbladder General Medicine Middle Aged medicine.disease Reverse transcription polymerase chain reaction Endocrinology medicine.anatomical_structure Gene Expression Regulation Female Rapid Communication Receptors Pituitary Adenylate Cyclase-Activating Polypeptide Type I |
Popis: | AIM: To detect the expression of pituitary adenylate cyclase-activating polypeptide receptor 1 (VPCAP1-R) and VPCAP2-R mRNA in gallbladder tissues of patients with gallstone or gallbladder polyps. METHODS: The expression of VPCAP1-R and VPCAP2-R mRNA in gallbladder tissues was detected in 25 patients with gallstone, 8 patients with gallbladder polyps and 7 donors of liver transplantation by reverse transcription polymerase chain reaction (RT-PCR). RESULTS: The VPCAP2-R mRNA expression level in the control group (1.09±0.58) was lower than that in the gallbladder polyp group (1.64 ± 0.56) and the gallstone group (1.55±0.45) (P |
Databáze: | OpenAIRE |
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