Intractable epilepsy due to meningitis: results of surgery and pathological findings
| Autor: | B. P. Hermann, K. G. Davies, F Dohan, Allen R. Wyler |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Hippocampus Functional Laterality Temporal lobe Central nervous system disease Epilepsy medicine Corpus callosotomy Humans Meningitis Gliosis Child Electrocorticography Anterior temporal lobectomy Retrospective Studies Hippocampal sclerosis Sclerosis medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Temporal Lobe Surgery Treatment Outcome Female Neurology (clinical) business Follow-Up Studies |
| Zdroj: | British journal of neurosurgery. 10(6) |
| ISSN: | 0268-8697 |
| Popis: | Between 1986 and 1992, among a total of 668 craniotomies performed for intractable epilepsy, 13 (1.9%) patients had a presumed aetiology of a previous episode of meningitis. Twelve were investigated with chronic electrocorticography with subdural electrodes which showed mesial temporal onset in eight, regional temporal onset in three and bilateral diffuse onset in one. One patient underwent corpus callosotomy and 12 anterior temporal lobectomy (ATL) (6L, 6R). The pathology in the resection cases was hippocampal sclerosis in six and gliosis in six. Mean length of follow up was 3 years (range 1-6 years). Ten of the 12 (83%) ATL patients were seizure free (six off medications). Two ATL patients and the callosotomy patient were significantly improved. It is concluded that in patients where the presumed aetiology of intractable epilepsy is meningitis and widespread damage may therefore be expected, this does not necessarily indicate multifocality, and the prognosis following resective surgery appears to be good. |
| Databáze: | OpenAIRE |
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