Identification of Patients with Intermediate Thickness Melanoma at Low Risk for Sentinel Lymph Node Positivity
| Autor: | Xiaowei G. Xu, DuPont Guerry, Phyllis A. Gimotty, Brian J. Czerniecki, Douglas L. Fraker, Anne Blair, Michael E. Ming, Mark S. Etherington, Giorgos C. Karakousis, Edmund K. Bartlett, David E. Elder, Madalyn G. Peters |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Skin Neoplasms Lymphovascular invasion Sentinel lymph node Gastroenterology Article 03 medical and health sciences 0302 clinical medicine Lymphocytes Tumor-Infiltrating Risk Factors Internal medicine Biopsy medicine Humans 030212 general & internal medicine Melanoma Neoplasm Staging Retrospective Studies medicine.diagnostic_test business.industry Sentinel Lymph Node Biopsy Retrospective cohort study Odds ratio Middle Aged medicine.disease Prognosis Confidence interval Oncology 030220 oncology & carcinogenesis Cohort Surgery Female Lymph Nodes Neoplasm Recurrence Local business Follow-Up Studies |
| Zdroj: | Annals of surgical oncology. 23(1) |
| ISSN: | 1534-4681 |
| Popis: | Sentinel lymph node (SLN) biopsy is recommended for all patients with intermediate-thickness melanomas. We sought to identify such patients at low risk of SLN positivity. All patients with intermediate-thickness melanomas (1.01–4 mm) undergoing SLN biopsy at a single institution from 1995–2011 were included in this retrospective cohort study. Univariate and multivariate logistic regression determined factors associated with a low risk of SLN positivity. Classification and regression tree (CART) analysis was used to stratify groups based on risk of positivity. Of the 952 study patients, 157 (16.5 %) had a positive SLN. In the multivariate analysis, thickness |
| Databáze: | OpenAIRE |
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