REFINAMIENTO DE LOS BIOMARCADORES DE MI-ARN DE LA SALIVA PARA LA CONMOCIÓN ENCEFÁLICA RELACIONADA CON EL DEPORTE
| Autor: | Cuifeng Gu, Guojian He, Chenhong Lin |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Revista Brasileira de Medicina do Esporte v.28 n.5 2022 Revista brasileira de medicina do esporte Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE) instacron:SBMEE Revista Brasileira de Medicina do Esporte, Volume: 28, Issue: 5, Pages: 469-473, Published: 13 MAY 2022 |
| ISSN: | 1806-9940 1517-8692 |
| DOI: | 10.1590/1517-8692202228052022_126 |
| Popis: | Introduction: The changes in brain structure caused by a sports-related concussion may initially be indistinguishable, however, the irreversible deleterious effects are noted in the long term. An early diagnosis may provide the patient with a better recovery chance and increased survival. For this purpose, this paper studies the feasibility of a diagnosis for concussion by microRNA (mi-RNA) biomarkers contained in the saliva of athletes. Objective: Verify whether salivary miRNAs could be considered good biomarkers for sports concussion. Methodology: Salivary mi-RNA levels were determined from 120 saliva samples of 120 players. There were 43 with a diagnosis of concussion and 77 without a diagnosis of concussion. Samples from players with a concussion were collected 30 minutes prior to activity, samples from individuals who did not engage in physical activity were also compared. Results: On the evaluation of 30 miRNA from individuals with a concussion between contact and non-contact sports there was high detection reliability(P |
| Databáze: | OpenAIRE |
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