Depression in Primary care: Interpersonal Counseling vs Selective serotonin reuptake inhibitors. The DEPICS Study. A multicenter randomized controlled trial. Rationale and design
| Autor: | Menchetti, M., Bortolotti, B., Rucci, P., Scocco, P., Bombi, A., Berardi, D., Affatati, V., Alberini, G., Baranzini, F., Bellino, S., Bellomo, A., Blasi, T., Bogetto, F., Bortolaso, P., Callegari, C., Carpiniello, B., Colombini, N., Contu, C., Croci, G., De Salvia, M., Diurni, M., Elisei, S., Ferretti, M., Fiore, P., Fusar-Poli, P., Iuso, S., Lacalamita, A., La Ferla, T., Lia, L., Luciano, C. C., Magnani, M., Manganaro, D., Martinelli, V., Martino, I., Montaguti, M. B., Nespeca, C., Petito, A., Pinna, F., Piselli, M., Politi, P., Quartesan, R., Rella, A., Restaino, F., Rigatelli, M., Sciarini, P., Simoni, E., Succui, M., Tedeschini, E., Todarello, O., Vender, S., Zaccagni, L., Zizza, M., Lullini, G., Pedrini, E., D'Onghia, A., Mazza, M., Papagni, S. |
|---|---|
| Přispěvatelé: | Menchetti M., Bortolotti B., Rucci P., Scocco P., Bombi A., Berardi D., DEPICS Study Group. |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Research design
Counseling Male NEUROPSYCHIATRIC INTERVIEW MINI Outcome Assessment Psychological intervention Personal Satisfaction law.invention Study Protocol STRUCTURED INTERVIEW Randomized controlled trial law lcsh:Psychiatry Surveys and Questionnaires Outcome Assessment Health Care Medicine Depression (differential diagnoses) METHODOLOGICAL ASPECTS OUTCOMES Depression Primary care Combined Modality Therapy Diagnostic and Statistical Manual of Mental Disorders Psychiatry and Mental health Selective serotonin reuptake inhibitors Treatment Outcome PSYCHOSOCIAL INTERVENTION Research Design Brief Serotonin Uptake Inhibitors Antidepressant Female Attitude to Health Selective Serotonin Reuptake Inhibitors Adult PROBLEM SOLVING TREATMENT medicine.medical_specialty Adolescent lcsh:RC435-571 DISORDERS Outcome Assessment (Health Care) Depressive Disorder Major Humans Primary Health Care Psychiatric Status Rating Scales Interpersonal Relations Psychotherapy Brief Quality of life (healthcare) QUALITY OF LIFE MAJOR DEPRESSION PSYCHOTHERAPY Psychiatry Intensive care medicine Depressive Disorder Primary Health Care Serotonin Uptake Inhibitors Psychotherapy Depressive Disorder business.industry Major Health Care Psychotherapy business |
| Zdroj: | BMC Psychiatry BMC Psychiatry, Vol 10, Iss 1, p 97 (2010) |
| Popis: | Background Depression is a frequently observed and disabling condition in primary care, mainly treated by Primary Care Physicians with antidepressant drugs. Psychological interventions are recommended as first-line treatment by the most authoritative international guidelines but few evidences are available on their efficacy and effectiveness for mild depression. Methods/Design This multi-center randomized controlled trial was conducted in 9 Italian centres with the aim to compare the efficacy of Inter-Personal Counseling, a brief structured psychological intervention, to that of Selective Serotonin Reuptake Inhibitors. Patients with depressive symptoms referred by Primary Care Physicians to psychiatric consultation-liaison services were eligible for the study if they met the DSM-IV criteria for major depression, had a score ≥13 on the 21-item Hamilton Depression Rating Scale, and were at their first or second depressive episode. The primary outcome was remission of depressive symptoms at 2-months, defined as a HDRS score ≤ 7. Secondary outcome measures were improvement in global functioning and recurrence of depressive symptoms at 12-months. Patients who did not respond to Inter-Personal Counseling or Selective Serotonin Reuptake Inhibitors at 2-months received augmentation with the other treatment. Discussion This trial addresses some of the shortcomings of existing trials targeting major depression in primary care by evaluating the comparative efficacy of a brief psychological intervention that could be easily disseminated, by including a sample of patients with mild/moderate depression and by using different outcome measures. Trial registration Australian New Zealand Clinical Trials Registry ACTRN12608000479303 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|