Sensitivity and Specificity of Transtympanic Electrocochleography in Meniere's Disease
| Autor: | Kornel Sass |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Audiology Sensitivity and Specificity Cochlear hearing loss otorhinolaryngologic diseases medicine Humans Endolymphatic hydrops Hearing Loss Hearing Disorders Meniere Disease Aged medicine.diagnostic_test business.industry General Medicine Middle Aged Electrocochleography medicine.disease Transtympanic electrocochleography Audiometry Evoked Response Otorhinolaryngology Clinical diagnosis Female sense organs Audiometry business Sensitivity (electronics) Meniere's disease |
| Zdroj: | Acta Oto-Laryngologica. 118:150-156 |
| ISSN: | 1651-2251 0001-6489 |
| DOI: | 10.1080/00016489850154838 |
| Popis: | Transtympanic electrocochleography (TT ECoG) was conducted in 61 patients (61 ears) with the clinical diagnosis of Meniere's disease and 15 patients (21 ears) with cochlear hearing loss of other aetiologies to assess the ability of the method to separate different cochlear disorders. The click-evoked summation potential/action potential (SP/AP) ratio and the 1 and 2 kHz burst-evoked SP amplitudes were evaluated. Based on the TT ECoG results from 13 normal hearing subjects (15 ears) the upper limit of each variable was determined, above which a value was considered pathological, i.e. indicative of endolymphatic hydrops. The results showed that the sensitivity of the SP/AP ratio was 62% and specificity 95%. When evaluating the combinations of TT ECoG parameters with logistic regression, SP/AP ratio and 1 kHz burst-evoked SP amplitude were shown to increase the discriminating ability of TT ECoG significantly. Inclusion of the 1 kHz burst-evoked SP amplitudes increased sensitivity to 82%, without changing specificity. Inclusion of the 2 kHz burst had no effect on sensitivity or specificity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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