Balo's concentric sclerosis: a clinical case
| Autor: | G. N. Bisaga, R. F. Gimadutdinov, I. V. Litvinenko, V. Yu. Lobzin, P. S. Dynin, V. S. Chirsky, S. Yu. Golokhvastov |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
concentric sclerosis
Pathology medicine.medical_specialty multiple sclerosis demyelinating disease Cerebrospinal fluid Neuroimaging neurohistology Biopsy immune histochemistry medicine Demyelinating disease RC346-429 medicine.diagnostic_test business.industry Brain biopsy Multiple sclerosis Magnetic resonance imaging medicine.disease Protoplasmic Astrocytoma Psychiatry and Mental health Clinical Psychology Neurology. Diseases of the nervous system Neurology (clinical) business balo's disease |
| Zdroj: | Nevrologiâ, Nejropsihiatriâ, Psihosomatika, Vol 10, Iss 3, Pp 97-102 (2018) |
| ISSN: | 2310-1342 2074-2711 |
| Popis: | This paper describes a case of Balo's concentric sclerosis, a rare demyelinating disease of the central nervous system (CNS), which is currently classified as multiple sclerosis. In recent years, there has been a more favorable clinical course of Balo's sclerosis. The significant polymorphism of clinical manifestations of the disease, its neuroimaging pattern, and laboratory tests cause difficulties diagnosing this pathology. Its differentiation with CNS tumors presents a particular challenge. So it also happens in the described clinical case, when computed tomography revealed the signs of space-occupying lesion, the histological pattern of concentric focus biopsy specimen indicated the presence of protoplasmic astrocytoma. However, immunohistochemical analyses of the biopsy specimen, immunological examination of cerebrospinal fluid, as well as the typical magnetic resonance imaging changes of Balo's sclerosis could suggest the demyelinating nature of the pathological process. The article shows that immunohistochemical techniques for examining a brain biopsy specimen and immunological assays of blood and cerebrospinal fluid are of great diagnostic value. |
| Databáze: | OpenAIRE |
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