Development of chiral potassium strong Brønsted base catalysts for enantioselective carbon–carbon bond-forming reactions

Autor:	Yasuhiro Yamashita
Rok vydání:	2022
Předmět:	Materials Chemistry Metals and Alloys Ceramics and Composites General Chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials
Zdroj:	Chemical Communications. 58:1078-1088
ISSN:	1364-548X 1359-7345
DOI:	10.1039/d1cc06328f
Popis:	Chiral alkaline metal Brønsted bases are traditional and reliable promoters in enantioselective catalysis. Here, new chiral potassium strong base catalysts were developed for enantioselective carbon-carbon bond-forming reactions of weakly acidic carbon pronucleophiles. Chiral potassium amide or alkyl potassium catalyzed enantioselective addition reactions to imines or α,β-unsaturated amides with good to high enantioselectivities. The good potential of chiral potassium Brønsted bases to act as proton transfer catalysts has been shown.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1ba1f2343c8233b38e3e0abcff7f08 https://doi.org/10.1039/d1cc06328f Zobrazit plný text záznamu