Nomograms for predicting adverse obstetric outcome in IVF pregnancy: A preliminary study
| Autor: | Anderson Loundou, Claire Sunyach, Blandline Courbiere, Alice Portal, Jeanne Perrin, Odile Lacroix-Paulmye |
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| Přispěvatelé: | Aix-Marseille Université - École universitaire de maïeutique Marseille Méditerranée (AMU EU3M), Aix Marseille Université (AMU), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UMR237-Aix Marseille Université (AMU)-Avignon Université (AU), Department of Gynecology-Obstetric and Reproductive Medicine, AP-HM, Hôpital La Conception, 13005 Marseille, France, Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Endometriosis Ovarian hyperstimulation syndrome Fertilization in Vitro [SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics nomogram 03 medical and health sciences 0302 clinical medicine Pregnancy medicine IVF pregnancy Humans 030212 general & internal medicine Retrospective Studies 030219 obstetrics & reproductive medicine In vitro fertilisation pregnancy outcome Obstetrics business.industry Obstetrics and Gynecology Nomogram medicine.disease Obesity 3. Good health Nomograms IVF Pregnancy Twin Observational study Female [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business |
| Zdroj: | Birth Birth, Wiley, 2021, 48 (2), pp.186-193. ⟨10.1111/birt.12528⟩ Birth, 2021, 48 (2), pp.186-193. ⟨10.1111/birt.12528⟩ |
| ISSN: | 0730-7659 1523-536X |
| DOI: | 10.1111/birt.12528⟩ |
| Popis: | International audience; Background: In a previous study, we showed that the obstetric complication rate after in vitro fertilization (IVF) pregnancy was 40%. The main objective of our study was to determine maternal prognosis factors that influence the IVF pregnancy outcome.Methods: We conducted an observational retrospective monocentric study between January 2014 and January 2018. Pregnancy over 22 gestational weeks (GW) obtained after IVF in our infertility clinic was included. Maternal characteristics and pregnancy outcome were collected.Results: Data from 498 IVF pregnancies were analyzed. The most significant maternal prognosis factors for obstetric complications were maternal age above 40 years (OR 3,0 [95% IC 1,30-7,09], P = 0,010), twin pregnancies (3.8 [95% IC 1.49-9.99], P = .005), daily maternal smoking above 10 cigarettes (7.1 [95% IC 1.22-41.74], P = .029), maternal obesity (2.2 [95% IC 1.19-4.07], P = .012), endometriosis stages III and IV (6.4 [95% IC 1.52-27.04], P = .011), and history of ovarian hyperstimulation syndrome (OHSS) in early pregnancy (5.7 [95% IC 1.29-24.74], P = .021). Risk increase was independent of pregnancy type (singleton or twin) and allowed the elaboration of 2 nomograms.Conclusions: Our study showed a link between some maternal factors and increase in obstetric complications after IVF. Screening of these factors during preconceptional visit is essential to identify at high-risk pregnancies and adapt their monitoring. |
| Databáze: | OpenAIRE |
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