Autor: |
Atsushi, Miki, Yasunaru, Sakuma, Hideyuki, Ohzawa, Akira, Saito, Yoshiyuki, Meguro, Jun, Watanabe, Kazue, Morishima, Kazuhiro, Endo, Hideki, Sasanuma, Atsushi, Shimizu, Alan Kawarai, Lefor, Yoshikazu, Yasuda, Naohiro, Sata |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
World Journal of Gastroenterology. 28:5614-5625 |
ISSN: |
1007-9327 |
Popis: |
Estimation of the functional reserve of the remnant liver is important to reduce morbidity and mortality.To estimate the functional reserve of the remnant liver in patients with hepatocellular carcinoma (HCC).We reviewed the medical records of 199 patients who underwent resection of HCC. Hepatic clearance of the remnant liver was calculated using fusion images ofTwenty-seven (30%) patients had major complications and 23 (12%) developed PHLF. The incidence of major complications increased with increasing albumin-bilirubin (ALBI) grade. The area under the curve values for hepatic clearance of the remnant liver, liver to heart-plus-liver radioactivity at 15 min (LHL15), and ALBI score predicting PHLF were 0.868, 0.629, and 0.655, respectively. The area under the curve for hepatic clearance of the remnant liver, LHL15, and ALBI score predicting major complications were 0.758, 0.594, and 0.647, respectively. The risk factors for PHLF and major complications were hepatic clearance of the remnant liver and intraoperative bleeding.The measurement of hepatic clearance may predict PHLF and major complications for patients undergoing resection of HCC. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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