Clinical impact of elevated tricuspid valve inflow gradients after transcatheter edge-to-edge tricuspid valve repair
| Autor: | Thomas J. Stocker, Danny Kupka, Daniel Braun, Martin Orban, Michael Nabauer, Nicole Karam, Christian Hagl, Mathias Orban, Steffen Massberg, Simon Deseive, Erik Bagaev, Jörg Hausleiter |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Treatment outcome Regurgitation (circulation) 030204 cardiovascular system & hematology Nyha class 03 medical and health sciences Postoperative Complications 0302 clinical medicine Internal medicine Humans Medicine 030212 general & internal medicine Cardiac Surgical Procedures TRICUSPID VALVE REPAIR Heart Valve Prosthesis Implantation Tricuspid valve business.industry Walking test Mitral Valve Insufficiency medicine.disease Tricuspid Valve Insufficiency Treatment Outcome medicine.anatomical_structure Heart failure Cohort Cardiology Tricuspid Valve Cardiology and Cardiovascular Medicine business |
| Zdroj: | EuroIntervention. 15:e1057-e1064 |
| ISSN: | 1969-6213 |
| Popis: | Aims The aim of this study was to compare the outcome of patients with a post-procedural tricuspid valve gradient (TVG) of >3 mmHg vs ≤3 mmHg after transcatheter edge-to-edge tricuspid valve repair (TTVR). Methods and results Between March 2016 and October 2018 we treated 145 patients with severe tricuspid regurgitation (TR) with TTVR by placing 2.2±0.7 clips per patient. Device success (TR reduction ≥1° to at least moderate) was achieved in 125 patients (86.2%). TTVR resulted in an elevated TVG >3 mmHg in 25 (17.2%) patients. Device success (84% vs 86.7%, p=0.9), number of clips implanted (2.3±0.7 vs 2.2±0.7, p=0.33), clinical improvement including NYHA class (III/IV 24% vs 28%, p=0.92) and increase in six-minute walking test at one month (67 m [IQR 5-103 m] vs 56 m [IQR 8-97 m], p=0.93), mortality (HR 1.07, 95% CI: 0.43-2.65, plogrank=0.88) and the combined endpoint mortality and hospitalisation for heart failure at one year (HR 1.07, 95% CI: 0.46-2.48, plogrank=0.88) were similar between patients with a TVG >3 mmHg versus patients with a TVG ≤3 mmHg. Conclusions A small cohort of patients demonstrated an elevated TVG higher than 3 mmHg at discharge. This elevation had no impact on clinical improvement, mortality or hospitalisation for heart failure. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|