Hospital outcomes in pediatric patients with Prader–Willi syndrome (PWS) undergoing orthopedic surgery: A 12-year analysis of national trends in surgical management and inpatient hospital outcomes
| Autor: | Joseph C. Brinkman, Kade S. McQuivey, Andrew S. Chung, Mohan V. Belthur, Justin L. Makovicka, Zachary K. Christopher, Michael R. Jones |
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| Rok vydání: | 2022 |
| Předmět: |
Pediatrics
medicine.medical_specialty Acute blood loss anemia Urinary system medicine.medical_treatment Diabetes mellitus medicine Humans Orthopedics and Sports Medicine Musculoskeletal Diseases Child Retrospective Studies Inpatients business.industry Incidence (epidemiology) Retrospective cohort study medicine.disease medicine.icd_9_cm_classification Hospitals Spinal Fusion Spinal fusion Orthopedic surgery Surgery Orthopedic Procedures business Prader-Willi Syndrome |
| Zdroj: | Journal of Orthopaedic Science. 27:1304-1308 |
| ISSN: | 0949-2658 |
| Popis: | Background The incidence of orthopedic disorders amongst patients with Prader–Willi Syndrome (PWS) is high when compared to the general pediatric population. The purpose of this retrospective study was to define the most commonly performed orthopedic procedures in pediatric patients with PWS and to characterize the peri-operative outcomes of these patients. Methods The Kids Inpatient Database (KID) was queried to collect data and identify all pediatric patients with PWS who underwent orthopedic procedures from 2001 to 2012. A total of 3684 patients with PWS were identified, 334 of who underwent an orthopedic procedure. Population demographics, comorbidities, and specific procedures undergone were defined. The incidences of postoperative complications and length of associated hospital stay were additionally evaluated. Results Mean age of patients in this sample was 10.33 years (SD 4.5). The most common comorbidities included obesity (18.1%), chronic pulmonary disease (14.1%), hypothyroidism (5.1%), hypertension (5.1%), and uncomplicated diabetes (4%). Common procedures were spinal fusion (165/334, 49%) and lower extremity procedures (50/334, 15%). Complications included acute blood loss anemia, device related complications, pneumonia, sepsis, and urinary tract infections. The overall complication rate was 35.6%. Average hospital lengths of stay for patients undergoing spinal fusion was 6.68 days (SD 4.13), lower extremity orthopedic procedure was 5.65 days (SD 7.4), and all other orthopedic procedures was 7.74 days (SD 16.3). Conclusions Orthopedic disorders are common in patients with PWS. Consequently, spinal fusions and lower extremity procedures are commonly performed in this patient population. Associated comorbid conditions may negatively impact surgical outcomes in these patients. This information should prove useful in the peri-operative management of patients with PWS undergoing orthopedic surgery and for shared decision making with families. |
| Databáze: | OpenAIRE |
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