Predicting the risk of sepsis and causative organisms following urinary stones removal using urinary versus stone and stent cultures
| Autor: | Amihay Nevo, Dor Golomb, David A. Lifshitz, Dafna Yahav |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male 0301 basic medicine Microbiology (medical) medicine.medical_specialty medicine.medical_treatment Urinary system 030106 microbiology Urine Bacteriuria Urinalysis Urinary Catheters Gastroenterology Sepsis Kidney Calculi 03 medical and health sciences Postoperative Complications 0302 clinical medicine Predictive Value of Tests Risk Factors Internal medicine medicine Humans Prospective Studies 030212 general & internal medicine Ureteroscopy Percutaneous nephrolithotomy Aged Bacteria medicine.diagnostic_test business.industry Stent General Medicine Middle Aged medicine.disease Infectious Diseases Urinary Tract Infections Female Stents Kidney stones business |
| Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases. 38:1313-1318 |
| ISSN: | 1435-4373 0934-9723 |
| DOI: | 10.1007/s10096-019-03555-6 |
| Popis: | The association between foreign objects in the urinary system and urinary tract infections (UTI) is well established. The incidence of bacteriuria in patient with urinary catheters increases as dwelling time lengthens. The presence of ureteral stents and kidney stones is also associated with increased risk for bacteriuria and urinary tract infection. The aim of this study was to assess the bacterial characteristics of urine culture (UC) and foreign body culture (FBC), the concordance between them, and to identify risk factors for postoperative infections, in order to improve the treatment in these patients, using a prospectively collected database of patients who underwent ureteroscopy or percutaneous nephrolithotomy (PCNL) for the treatment of urinary stones between 2005 and 2016 at our institute. Preoperative UC was obtained from voided mid-stream urine for all patients. FBCs were obtained from ureteral stents removed and stones collected during the surgery. The cohort included 1011 patients. Mean age was 53 (SD 15.8), and 679 (67.2%) patients were male. Two hundred eighteen (21.6%) had a UTI in the year prior to the surgery. Among 795 patients who had sterile UC, 98 (12.3%) patients had positive FBC. Positive FBC was found in 53.7% of the patients with positive UC; however, FBC pathogens were similar to those identified in UC in 31% patients. The sensitivity of UC to detect FBC pathogens was 31.3%, and the PPV was 0.31. Urine cultures do not recognize all cases of pathogens colonizing foreign bodies in the urinary system. The colonization may be associated with an increased risk for SIRS. In more than one-quarter of the patients, the causative pathogen of sepsis is identified by FBC, but not by UC. |
| Databáze: | OpenAIRE |
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