Extended Lung Ultrasound to Differentiate Between Pneumonia and Atelectasis in Critically Ill Patients: A Diagnostic Accuracy Study
| Autor: | Mark E. Haaksma, Harm Jan de Grooth, Annemijn H. Jonkman, Armand R. J. Girbes, Leo M. A. Heunks, Jip S. Nooitgedacht, Pieter R. Tuinman, Micah L A Heldeweg, Jasper M Smit |
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| Přispěvatelé: | Intensive care medicine, ACS - Pulmonary hypertension & thrombosis, Radiology and nuclear medicine, ACS - Diabetes & metabolism, Anesthesiology, ACS - Microcirculation, AII - Infectious diseases |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Pulmonary Atelectasis Critical Illness Atelectasis Diagnostic accuracy Critical Care and Intensive Care Medicine Sensitivity and Specificity Pulmonary consolidation medicine Humans Prospective Studies Lung Ultrasonography medicine.diagnostic_test business.industry Critically ill COVID-19 Pneumonia medicine.disease Lung ultrasound medicine.anatomical_structure Radiology medicine.symptom Chest radiograph business |
| Zdroj: | Critical Care Medicine, 50(5), 750-759. Lippincott Williams and Wilkins Haaksma, M E, Smit, J M, Heldeweg, M L A, Nooitgedacht, J S, de Grooth, H J, Jonkman, A H, Girbes, A R J, Heunks, L & Tuinman, P R 2022, ' Extended Lung Ultrasound to Differentiate between Pneumonia and Atelectasis in Critically Ill Patients : A Diagnostic Accuracy Study ', Critical Care Medicine, vol. 50, no. 5, pp. 750-759 . https://doi.org/10.1097/CCM.0000000000005303 |
| ISSN: | 1530-0293 0090-3493 |
| DOI: | 10.1097/CCM.0000000000005303 |
| Popis: | Objectives To determine the diagnostic accuracy of extended lung ultrasonographic assessment, including evaluation of dynamic air bronchograms and color Doppler imaging to differentiate pneumonia and atelectasis in patients with consolidation on chest radiograph. Compare this approach to the Simplified Clinical Pulmonary Infection Score, Lung Ultrasound Clinical Pulmonary Infection Score, and the Bedside Lung Ultrasound in Emergency protocol. Design Prospective diagnostic accuracy study. Setting Adult ICU applying selective digestive decontamination. Patients Adult patients that underwent a chest radiograph for any indication at any time during admission. Patients with acute respiratory distress syndrome, coronavirus disease 2019, severe thoracic trauma, and infectious isolation measures were excluded. Interventions None. Measurements and main results Lung ultrasound was performed within 24 hours of chest radiograph. Consolidated tissue was assessed for presence of dynamic air bronchograms and with color Doppler imaging for presence of flow. Clinical data were recorded after ultrasonographic assessment. The primary outcome was diagnostic accuracy of dynamic air bronchogram and color Doppler imaging alone and within a decision tree to differentiate pneumonia from atelectasis. Of 120 patients included, 51 (42.5%) were diagnosed with pneumonia. The dynamic air bronchogram had a 45% (95% CI, 31-60%) sensitivity and 99% (95% CI, 92-100%) specificity. Color Doppler imaging had a 90% (95% CI, 79-97%) sensitivity and 68% (95% CI, 56-79%) specificity. The combined decision tree had an 86% (95% CI, 74-94%) sensitivity and an 86% (95% CI, 75-93%) specificity. The Bedside Lung Ultrasound in Emergency protocol had a 100% (95% CI, 93-100%) sensitivity and 0% (95% CI, 0-5%) specificity, while the Simplified Clinical Pulmonary Infection Score and Lung Ultrasound Clinical Pulmonary Infection Score had a 41% (95% CI, 28-56%) sensitivity, 84% (95% CI, 73-92%) specificity and 68% (95% CI, 54-81%) sensitivity, 81% (95% CI, 70-90%) specificity, respectively. Conclusions In critically ill patients with pulmonary consolidation on chest radiograph, an extended lung ultrasound protocol is an accurate and directly bedside available tool to differentiate pneumonia from atelectasis. It outperforms standard lung ultrasound and clinical scores. |
| Databáze: | OpenAIRE |
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