Artemisinin drugs in the treatment of malaria
| Autor: | Teunis A. Eggelte, Michiel A. van Agtmael, Chris J. van Boxtel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1999 |
| Předmět: |
Artemisia annua
Pharmacology Toxicology chemistry.chemical_compound Herbal tea Antimalarials Pharmacokinetics parasitic diseases medicine Animals Humans Artemether Artemisinin Adverse effect Drug Approval Clinical Trials as Topic Plants Medicinal biology Traditional medicine business.industry food and beverages biology.organism_classification medicine.disease Artemisinins Malaria Treatment Outcome chemistry Artemisia Artesunate business Sesquiterpenes medicine.drug Forecasting |
| Zdroj: | Van Agtmael, M A, Eggelte, T A & Van Boxtel, C J 1999, ' Artemisinin drugs in the treatment of malaria : From medicinal herb to registered medication ', Trends in Pharmacological Sciences, vol. 20, no. 5, pp. 199-205 . https://doi.org/10.1016/S0165-6147(99)01302-4 |
| ISSN: | 0165-6147 |
| DOI: | 10.1016/S0165-6147(99)01302-4 |
| Popis: | Registration in Europe of several artemisinin drugs for the treatment of malaria can soon be expected. Artemisinin is isolated from the herb Artemisia annua , in use in China more than 2000 years as a herbal tea against fever. Artemisinin drugs are being used extensively in South-East Asia and increasingly in Africa. Active derivatives have been synthesized – artemether, arteether and artesunate – which are used for oral, intramuscular, rectal and intravenous administration. The origin, mechanism of action, efficacy and safety in patients, the pharmacokinetics and the position of this group of compounds among existing antimalarials are discussed in this review. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect