The history, physiology and treatment safety of growth hormone
| Autor: | Anders Tidblad |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Physiology
Growth hormone Short stature Growth hormone deficiency 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Medicine Humans 030212 general & internal medicine Child Dwarfism Pituitary Growth Disorders Endogenous growth theory business.industry Human Growth Hormone Cancer General Medicine medicine.disease Body Height Growth hormone treatment Growth Hormone Pediatrics Perinatology and Child Health Long term safety medicine.symptom business Hormone |
| Zdroj: | Acta paediatrica (Oslo, Norway : 1992)REFERENCES. 111(2) |
| ISSN: | 1651-2227 |
| Popis: | Growth hormone treatment was introduced in the 1950s to address growth disturbances and metabolic abnormalities. Hundreds of thousands of children have been treated, with gradual expansion of treatment indications. From initially being offered only to patients with severe growth hormone deficiency, today many children are treated for conditions in which the associated short stature is not primarily thought to be due to deficient endogenous growth hormone secretion. This review discusses the history, physiology and safety of growth hormone treatment, with focus on the long-term risks of mortality, cardiovascular morbidity and cancer. Conclusion: Continuous follow-up is needed to increase our knowledge of the long-term treatment safety. |
| Databáze: | OpenAIRE |
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