Multiattribute Analysis of Trichomonas vaginalis Diagnostics and Its Correlation with Clinical Complaints and Contraceptive Methods in a Symptomatic Egyptian Cohort
| Autor: | Doaa Alaa, Marwa M. I. Ghallab, Salwa M. Morsy |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Vaginal discharge
Adult medicine.medical_specialty Article Subject Adolescent 030231 tropical medicine Trichomonas Infection Trichomonas Infections Dermatology Infectious and parasitic diseases RC109-216 Intrauterine device medicine.disease_cause Sensitivity and Specificity Giemsa stain 03 medical and health sciences Young Adult 0302 clinical medicine Pregnancy medicine Trichomonas vaginalis Outpatient clinic Humans 030212 general & internal medicine Univariate analysis Trichomoniasis business.industry Obstetrics Obstetrics and Gynecology Gynecology and obstetrics Middle Aged medicine.disease Infectious Diseases Contraception Cross-Sectional Studies RG1-991 Egypt Female medicine.symptom business Trichomonas Vaginitis Research Article |
| Zdroj: | Infectious Diseases in Obstetrics and Gynecology Infectious Diseases in Obstetrics and Gynecology, Vol 2021 (2021) |
| ISSN: | 1098-0997 1064-7449 |
| Popis: | Background. Trichomonas vaginalis (T. vaginalis) infection has been long considered among the sexually transmitted diseases that possesses a clear effect on women’s health especially in the childbearing period. Methods. A 234 females of age range 18-45 years old attending the Gynecology and Obstetrics Outpatient Clinic of Kasr El Aini Hospitals were enrolled in a cross-sectional study. The taken vaginal swabs were subjected to wet mount microscopy, Giemsa stain, modified Diamond’s culture, and nested polymerase chain reaction (nPCR) amplification. Multiattribute and analytical hierarchy processes were conducted to detect laboratory utility. Univariate and multivariate analyses were done to detect the multiple risk factors that may be associated with Trichomonas infection. Results. Based on nPCR, the prevalence of trichomoniasis was 26.9%. Wet mount, Giemsa stain, and culture showed 100% specificity but of low sensitivity (28.57%, 28.57%, and 57.14%, respectively). On the multivariate analysis, nPCR showed the highest rank for diagnostic performance and culture had the lowest rank. For univariate analysis, there was a significant correlation between T. vaginalis infection and vaginal discharge, burning sensation, dyspareunia, and the use of intrauterine device (IUD) (Pvalue < 0.05). Conclusion. The routine screening of trichomoniasis using nPCR was reliable, sensitive, and specific. Also, it could financially be considered a more suitable option in batch screening. Significant higher rates of infection were reported among IUD users compared to condom or hormonal-based methods. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text