Erythrocyte nucleotides and blood hypoxanthine in patients with uremia evaluated immediately and 24 hours after hemodialysis
| Autor: | Jacek Manitius, R. T. Smolenski, Julian Swierczynski, Bolesław Rutkowski, Maciej Marlewski, Barbara Bułło |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Erythrocytes Time Factors medicine.medical_treatment Critical Care and Intensive Care Medicine chemistry.chemical_compound Adenine nucleotide Renal Dialysis Internal medicine medicine Humans Nucleotide Dialysis Hypoxanthine Chromatography High Pressure Liquid Uremia chemistry.chemical_classification Analysis of Variance business.industry Nucleotides General Medicine Middle Aged medicine.disease Adenosine Endocrinology chemistry Biochemistry Nephrology Hypoxanthines Female Hemodialysis business Adenosine triphosphate medicine.drug |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0886-022X |
| Popis: | Using high-performance liquid chromatography, concentrations of erythrocyte adenine nucleotides and hypoxanthine were evaluated in patients undergoing regular acetate hemodialysis before dialysis, immediately following dialysis, and 24 hr after. It was shown that adenosine triphosphate concentration was maintained consistently high, not only just after hemodialysis but also 24 hr later. There was also no difference in concentration of mono- and diphosphates of adenosine. Hypoxanthine concentration decreased twofold after hemodialysis. However, it was still markedly higher than normal values. The level of hypoxanthine was maintained at the postdialysis level, 24 hr later. This suggests that hypoxanthine production could be stimulated during acetate dialysis. |
| Databáze: | OpenAIRE |
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