Pertussis: New preventive strategies for an old disease

Autor: Greta Di Mattia, Fabio Midulla, Raffaella Nenna, Laura Petrarca, Ambra Nicolai, Antonella Frassanito
Rok vydání: 2019
Předmět:
Adult
Pulmonary and Respiratory Medicine
Pediatrics
medicine.medical_specialty
Bordetella pertussis
Vaccination Coverage
Adolescent
epidemics
infants
pertussis
prevention
pediatrics
perinatology and child health
pulmonary and respiratory medicine
pediatrics
Whooping Cough
Immunization
Secondary
Disease
Asymptomatic
Cocooning (immunization)
03 medical and health sciences
Vaccines
Acellular
0302 clinical medicine
Pregnancy
030225 pediatrics
medicine
Humans
Family
Pertussis Vaccine
biology
Transmission (medicine)
business.industry
Incidence (epidemiology)
Vaccination
Infant
Newborn
Infant
biology.organism_classification
medicine.disease
Anti-Bacterial Agents
030228 respiratory system
Pediatrics
Perinatology and Child Health
perinatology and child health
Female
medicine.symptom
business
Immunity
Maternally-Acquired
Developed country
Zdroj: Paediatric Respiratory Reviews. 29:68-73
ISSN: 1526-0542
DOI: 10.1016/j.prrv.2018.03.011
Popis: In the last twenty years, despite high vaccination coverage, epidemics of pertussis are occurring in both developing and developed countries. Many reasons could explain the pertussis resurgence: the increasing awareness of the disease, the availability of new diagnostic tests with higher sensitivity, the emergence of new Bordetella pertussis (B. pertussis) strains different from those contained in the current vaccines, the asymptomatic transmission of B. pertussis in adolescents and adults and the shorter duration of protection given by the acellular pertussis (aP) vaccine. New preventive strategies have already been implemented, such as booster doses of aP vaccine in adolescents and adults, maternal immunisation during pregnancy and the "cocooning" strategy, but more are still needed. Knowing what is new about this old disease is necessary to reduce its incidence and to protect infants too young to be vaccinated, which have the highest risk of complications and death.
Databáze: OpenAIRE
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