Platelets and carbon clearance rates in rabbits affected by a tubercle bacillary lipid or endotoxin
| Autor: | K. J. Donald, Eveline van’t Hull |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Blood Platelets
medicine.medical_specialty Platelet Numbers Time Factors Tubercle chemistry.chemical_element Pathology and Forensic Medicine Carbon particle Internal medicine medicine Animals Platelet Colloids Chemistry Macrophages Mycobacterium tuberculosis Lipids Carbon Blood Cell Count Endotoxins Endocrinology Immunology Female Rabbits Clearance rate |
| Zdroj: | Virchows Archiv B Cell Pathology. 13:169-178 |
| ISSN: | 0340-6075 |
| DOI: | 10.1007/bf02889306 |
| Popis: | The changes in the number of circulating platelets and in the carbon clearance rates of rabbits given colloidal carbon alone or at various times after a tubercle bacillary lipid or endotoxin were studied. The results provide further evidence of the importance of platelet numbers and function in the control of carbon clearance rates in normal and experimental circumstances. Soon after the tubercle lipid or the endotoxin injections the number of circulating platelets fell to low levels and carbon clearance rates were slow. The number of circulating platelets then recovered to approximately half of resting levels at 4 hrs after either the lipid or the endotoxin and the carbon clearance rates became elevated. The clearance rates now showed biphasic characteristics which have previously been shown to be associated with increased attachment of carbon particles to platelets as well as macrophages. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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