Comparative detectability of bone metastases and impact on therapy of magnetic resonance imaging and bone scintigraphy in patients with breast cancer
| Autor: | Nadir Ghanem, Ernst Moser, Stefan Högerle, Mathias Langer, Carsten Altehoefer |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
Time Factors Axial skeleton Mammary gland Bone Neoplasms Breast Neoplasms Scintigraphy Metastasis Diagnosis Differential Breast cancer medicine Humans Radiology Nuclear Medicine and imaging Radionuclide Imaging Pelvis Retrospective Studies Spinal Neoplasms medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Bone scintigraphy Female Radiology business Nuclear medicine |
| Zdroj: | European Journal of Radiology. 40:16-23 |
| ISSN: | 0720-048X |
| DOI: | 10.1016/s0720-048x(01)00313-8 |
| Popis: | Objective: to evaluate the comparative impact of magnetic resonance imaging and bone scintigraphy in bone metastases of breast cancer. Methods and patients: in 81 patients with histologically proven breast cancer magnetic resonance imaging of the axial skeleton and whole-body bone scintigraphy had been performed. Images were retrospectively reviewed and compared for detection of metastases, extent of metastatic disease and therapeutic implications according to the patients’ records. Results: about 54/81 (67%) patients revealed bone metastases. In 7/54 (13%) patients with bone metastases, scintigraphy was false negative. In one patient a solitary sternal metastases was seen. In 26/53 [49%] patients with spinal metastases, magnetic resonance imaging showed more extensive disease. Local radiotherapy or surgery was indicated in ten patients with metastases not evident in bone scintigraphy, in 20 patients with positive results by both imaging modalities and in six patients with metastases of pelvis imaged by bone scintigraphy only. Conclusion: magnetic resonance imaging of the axial skeleton and pelvis appears superior for staging as only one patient had metastases merely outside the axial skeleton and local therapy was indicated even in spinal regions negative in bone scintigraphy. |
| Databáze: | OpenAIRE |
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