Post-stroke Spasticity: A Review of Epidemiology, Pathophysiology, and Treatments
| Autor: | Gwo-Chi Hu, Chih-Lin Kuo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
030506 rehabilitation
medicine.medical_specialty business.industry Mechanism (biology) Caregiver burden lcsh:Geriatrics Botulinum toxin 03 medical and health sciences lcsh:RC952-954.6 0302 clinical medicine medicine.anatomical_structure Physical medicine and rehabilitation Disinhibition Medicine Stretch reflex Joint Contracture Spasticity Geriatrics and Gerontology medicine.symptom 0305 other medical science business 030217 neurology & neurosurgery Neurolysis medicine.drug |
| Zdroj: | International Journal of Gerontology, Vol 12, Iss 4, Pp 280-284 (2018) |
| ISSN: | 1873-9598 |
| Popis: | Summary: Spasticity is a common condition in stroke survivors, and may be associated with pain and joint contracture, leading to poor quality of life and increased caregiver burden. Although the underlying mechanisms are not well-understood, it may be due to disruption of the balance of supra-spinal inhibitory and excitatory sensory inputs directed to the spinal cord, leading to a state of disinhibition of the stretch reflex. The treatment options include physical therapy, modality and pharmacological treatments, neurolysis with phenol and botulinum toxin, and surgical treatment. A successful treatment of spasticity depends on a clear comprehension of the underlying pathophysiology, natural history, and impact on patient's performances. This review focuses on the epidemiology, presumed mechanism, clinical manifestation, and recent evidences of management. Keywords: stroke, muscle spasticity, mechanism, symptom management |
| Databáze: | OpenAIRE |
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