The Relationship of Psychiatric Symptoms with Performance-Based and Self-Reported Cognitive Function After Ischemic Stroke
| Autor: | Linas A. Bieliauskas, Paulina Due-Tønnessen, Truls Ryum, Bente Thommessen, Elise Gjestad, Alexander Olsen, Tormod Fladby, Bent Indredavik, Elisabeth Kliem, Ramune Grambaite |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Neuropsychological Tests Hospital Anxiety and Depression Scale Brain Ischemia Cognition medicine Humans Cognitive Dysfunction Neuropsychological assessment Psychiatry Stroke Depression (differential diagnoses) Aged Ischemic Stroke medicine.diagnostic_test business.industry General Neuroscience Neuropsychology Middle Aged medicine.disease Psychiatry and Mental health Clinical Psychology Ischemic stroke Anxiety Self Report Neurology (clinical) medicine.symptom business |
| Zdroj: | Journal of the International Neuropsychological Society |
| ISSN: | 1469-7661 1355-6177 |
| DOI: | 10.1017/s1355617721000187 |
| Popis: | Objective:Findings on the relationship of psychiatric symptoms with performance-based and self-reported cognitive function post-stroke are inconclusive. We aimed to (1) study the relation of depression and anxiety to performance-based cognitive function and (2) explore a broader spectrum of psychiatric symptoms and their association with performance-based versus self-reported cognitive function.Method:Individuals with supratentorial ischemic stroke performed neuropsychological examination 3 months after stroke. For primary analyses, composite scores for memory and attention/executive function were calculated based on selected neuropsychological tests, and the Hospital Anxiety and Depression Scale (HADS) was used. Psychiatric symptoms and self-reported cognitive function for secondary aims were assessed using the Symptom-Checklist-90 – Revised (SCL-90-R).Results:In a sample of 86 patients [mean (M) age: 64.6 ± 9.2; Mini-Mental State Examination (MMSE), 3–7 days post-stroke: M = 28.4 ± 1.7; National Institutes of Health Stroke Scale (NIHSS) after 3 months: M = 0.7 ± 1.6] depressive symptoms (HADS) were associated with poorer memory performance after controlling for age, sex, and education (p ≤ .01). In a subsample (n = 41; Age: M = 65.7 ± 8.1; MMSE: M = 28.4 ± 1.8; NIHSS: M = 1.0 ± 1.9), symptoms of phobic anxiety (SCL-90-R) were associated with poorer performance-based memory and attention/executive function, and symptoms of anxiety (SCL-90-R) with lower attention/executive function. Higher levels of self-reported cognitive difficulties were associated with higher scores in all psychiatric domains (p ≤ .05).Conclusion:Even in relatively well-functioning stroke patients, depressive symptoms are associated with poorer memory. The results also suggest that various psychiatric symptoms are more related to self-reported rather than to performance-based cognitive function. Screening for self-reported cognitive difficulties may not only help to identify patients with cognitive impairment, but also those who need psychological treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|