Discovery of two novel (4-hydroxyphenyl) substituted polycyclic carbocycles as potent and selective estrogen receptor beta agonists

Autor:	Edward A, Wetzel, Kylee J, Marks, Alexandra A, Gleason, Sandra, Brown-Ford, Terry-Elinor, Reid, Subhabrata, Chaudhury, Sergey, Lindeman, Daniel S, Sem, William A, Donaldson
Rok vydání:	2022
Předmět:	Phenols Organic Chemistry Clinical Biochemistry Drug Discovery Estrogen Receptor alpha Estrogen Receptor beta Pharmaceutical Science Molecular Medicine Estrogens Molecular Biology Biochemistry
Zdroj:	Bioorganic & Medicinal Chemistry Letters. 73:128906
ISSN:	0960-894X
DOI:	10.1016/j.bmcl.2022.128906
Popis:	Two (4-hydroxyphenyl) substituted polycyclic carbocycles were prepared and assayed for estrogen receptor activity. 4-(4-Hydroxyphenyl)tricyclo[3.3.1.1
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d22e8845e649050b0124bb1308cea0 https://doi.org/10.1016/j.bmcl.2022.128906 Zobrazit plný text záznamu Full Text from ScienceDirect