A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission
| Autor: | Ferdinand Roesch, Olivier Schwartz, Marine Malbec |
|---|---|
| Přispěvatelé: | Virus et Immunité, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
virological synapses
viruses [SDV]Life Sciences [q-bio] lcsh:QR1-502 Biology p12 lcsh:Microbiology Cell Line 03 medical and health sciences 0302 clinical medicine Cell to cell transmission p8 Virology Humans Viral Regulatory and Accessory Proteins 030304 developmental biology Human T-lymphotropic virus 1 0303 health sciences Nef cellular conduits virus diseases biology.organism_classification HTLV-I Infections 3. Good health Cell biology Infectious Diseases Cell culture HTLV-1 HTLV-I infections Commentary HIV-1 Intracellular 030215 immunology cell-to-cell transfer |
| Zdroj: | Viruses Viruses, MDPI, 2011, 3 (3), pp.254-259. ⟨10.3390/v3030254⟩ Viruses, Vol 3, Iss 3, Pp 254-259 (2011) Viruses, 2011, 3 (3), pp.254-259. ⟨10.3390/v3030254⟩ |
| ISSN: | 1999-4915 |
| DOI: | 10.3390/v3030254⟩ |
| Popis: | International audience; Retroviruses like HIV-1 and HTLV-1 can be transmitted efficiently by direct contact between infected and target cells. For HIV-1, various modes of cell-to-cell transfer have been reported, including virological synapses, polysynapses, filopodial bridges, and nanotube-like structures. So far, only synapses and biofilms have been described for HTLV-1 transmission. Recently, Van Prooyen et al. [1] identified an additional mode of HTLV-1 transmission through cellular conduits induced by the viral accessory protein p8. |
| Databáze: | OpenAIRE |
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