Disseminated Bone Marrow Carcinomatosis Due to Malignant Melanoma of Unknown Primary Origin
Autor: | Shinpei Doi, Takayuki Tsujikawa, Go Saito, Hiromichi Tsunashima, Takako Adachi, Tomohiro Kikuyama, Ayako Watanabe, Kotaro Matsumoto, Ken Sato, Kentaro Kikuchi |
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Rok vydání: | 2021 |
Předmět: |
Pathology
medicine.medical_specialty Myeloid Carcinosis malignant melanoma Case Report 030204 cardiovascular system & hematology Liver disorder 03 medical and health sciences 0302 clinical medicine Bone Marrow Biopsy Internal Medicine medicine Humans Melanoma Peritoneal Neoplasms Aged 80 and over Disseminated intravascular coagulation medicine.diagnostic_test business.industry disseminated carcinomatosis of the bone marrow General Medicine Disseminated Intravascular Coagulation CD79a medicine.disease Thrombosis medicine.anatomical_structure Neoplasms Unknown Primary Female 030211 gastroenterology & hepatology Bone marrow Bone Marrow Neoplasms business unknown primary origin |
Zdroj: | Internal Medicine |
ISSN: | 1349-7235 0918-2918 |
DOI: | 10.2169/internalmedicine.7274-21 |
Popis: | An 80-year-old woman was admitted to our hospital due to appetite loss and vomiting. A blood examination showed liver disorder with disseminated intravascular coagulation. All tumor markers and hepatitis virus markers were negative. Contrast-enhanced computed tomography did not show tumor lesions, bone lesions, lymphadenopathies, or thrombosis. A bone marrow biopsy revealed large, atypical cells with brown pigmentation and positive immunostaining for HMB-45, S100 proteins, and CD79a without myeloid or lymphoid markers. We experienced a case of disseminated carcinomatosis of the bone marrow due to malignant melanoma of unknown primary origin. |
Databáze: | OpenAIRE |
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