Determination of iodoacetic acid using liquid chromatography/electrospray tandem mass spectrometry
| Autor: | Adam Becalski, Benjamin P.-Y. Lau |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Detection limit
Spectrometry Mass Electrospray Ionization Electrospray Chromatography Iodoacetic acid Electrospray ionization Organic Chemistry Water chemistry.chemical_element Tandem mass spectrometry Iodine Sensitivity and Specificity Gas Chromatography-Mass Spectrometry Iodoacetic Acid Analytical Chemistry chemistry.chemical_compound chemistry Tap water Tandem Mass Spectrometry Calibration Derivatization Spectroscopy Chromatography Liquid |
| Zdroj: | Rapid Communications in Mass Spectrometry. 22:1787-1791 |
| ISSN: | 1097-0231 0951-4198 |
| DOI: | 10.1002/rcm.3547 |
| Popis: | A rapid analytical method based on liquid chromatography/tandem mass spectrometry (LC/MS/MS) using electrospray ionization in negative ion detection mode was developed for the analysis of underivatized iodoacetic acid in water. The method was applied to model reaction mixtures in the study of the formation of iodoacetic acid after chlorinated tap water was boiled in the presence of potassium iodide or iodized table salt. Samples can be directly analyzed by the LC/MS/MS system without extraction or chemical derivatization. Limit of detection was determined to be 0.3 µg/L (or 0.3 ng/mL) and limit of quantitation was about 1 µg/L (1 ng/mL). Copyright © 2008 John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
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