IgA Nephropathy with Dominant IgA2 Deposition Accompanied by Mantle Cell Lymphoma
| Autor: | Teruhiko Imamura, Hidenori Yamazaki, Tsutomu Koike, Shiori Kobayashi, Koichiro Kinugawa, Hayato Fujioka, Kota Kakeshita, Akinori Wada |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
renal infiltration
Adult Male Pathology medicine.medical_specialty medicine.medical_treatment Kidney Glomerulus Case Report Lymphoma Mantle-Cell 030204 cardiovascular system & hematology IgA subclass Nephropathy Malignant lymphoma 03 medical and health sciences 0302 clinical medicine immune system diseases hemic and lymphatic diseases Internal Medicine medicine Humans Rapidly progressive glomerulonephritis rapidly progressive glomerulonephritis Aged Chemotherapy Nephritis business.industry Glomerulonephritis IGA General Medicine medicine.disease Immunoglobulin A Lymphoma Colonic mucosa 030211 gastroenterology & hepatology Mantle cell lymphoma business |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.6099-20 |
| Popis: | Malignant lymphoma is rarely complicated by secondary IgA nephropathy. We encountered a 74-year-old man with rapidly progressive glomerulonephritis due to IgA nephropathy with predominant deposition of IgA2, instead of IgA1, in the glomerulus that was eventually diagnosed as secondary IgA nephropathy due to mantle cell lymphoma. Renal impairment was improved by chemotherapy for the mantle cell lymphoma. IgA came from the colonic mucosa that was stimulated by the infiltrated lymphoma cells, instead of the tumor itself. We should consider mantle cell lymphoma as a cause of secondary IgA nephropathy, although its prevalence may not be very high. |
| Databáze: | OpenAIRE |
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