BONE MARROW IRON STORE IN PERLS’ STAINED ASPIRATES AND THE RED CELL INDICES
| Autor: | Laishram Rajesh Singh, Kaushik Debnath, Ningthoujam Bhubon Singh, Laishram Deepak Kumar, Gurumayum Laxmikanta Sharma |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Journal of Evidence Based Medicine and Healthcare, Vol 4, Iss 64, Pp 3830-3835 (2017) |
| ISSN: | 2349-2570 2349-2562 |
| Popis: | BACKGROUND The National Family Health Survey 3 (NFHS-3) states the prevalence of anaemia in India to be 55.3% in women and 24.2% in men. The evaluation of Bone Marrow (BM) iron is a sensitive and reliable means for the diagnosis of iron deficiency anaemia. BM iron identified by Perls’ Prussian blue reaction is regarded as the gold standard for evaluating BM iron stores. Surrogate serum biochemical markers are routinely employed to assess the BM iron status. Among the automated cell counter parameters, increase in the RDW is the earliest evidence of iron deficiency. Hb level, RBC count, PCV, MCV, MCH and MCHC values fall progressively with time. Our study was commenced with an intent to evaluate the Bone Marrow (BM) iron status in different haematological disorders and to correlate it with the peripheral blood red cell indices. MATERIALS AND METHODS BM aspirations of 100 patients were done. The Perls’ stained smears were evaluated and graded for BM iron stores. Using ABX Pentra 60 automatic cell analyser, RBC indices were determined from the peripheral blood samples. RESULTS Significant and fair correlations of MCV (rs = 0.317, n=100, p |
| Databáze: | OpenAIRE |
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