Malarial Immunity in Pregnant Nigerian Women and Their Newborn
| Autor: | A.I.O. Williams, P.A. Ibeziako, A.A. Okerengwo |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
medicine.medical_specialty
Fluorescent Antibody Technique Nigeria Gestational Age Antibodies Antimalarials 03 medical and health sciences 0302 clinical medicine Pregnancy Immunity medicine Last Trimesters Humans 030212 general & internal medicine Pregnancy Complications Infectious 030219 obstetrics & reproductive medicine Obstetrics business.industry Infant Newborn Antibody titer Obstetrics and Gynecology Gestational age General Medicine Fetal Blood medicine.disease Malaria Chemoprophylaxis Immunology Female business |
| Zdroj: | International Journal of Gynecology & Obstetrics. 18:147-149 |
| ISSN: | 0020-7292 |
| Popis: | The levels of malarial fluorescent antibody titers (MFAT) were estimated throughout pregnancy and at delivery in 20 urban Nigerian primigravidas who received malarial chemoprophylaxis. There was a statistically significant (p < 0.001) fall in the MFAT levels as pregnancy progressed. The mean logarithmic MFAT levels were 2.8664 +/- 0.3326 and 2.2794 +/- 0.1656 in the first and last trimesters of pregnancy, respectively. The MFAT level in the newborn was positively correlated to the maternal MFAT level at delivery (r = 0.9468; p < 0.001). If malarial prophylactics are used for a prolonged period, the maternal MFAT level will fall, leaving newborns with lowered immunity to malaria. |
| Databáze: | OpenAIRE |
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