Dog factor differences in Can f 1 allergen production
| Autor: | M. Ramadour, D. Vervloet, M. Guetat, J. Guetat, M. El Biaze, Antoine Magnan |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Veterinary medicine Immunology biology.animal_breed Pyrenean shepherd Animal science Dogs Sex Factors Species Specificity Immunology and Allergy Medicine Animals Humans Castration Dog Diseases Yorkshire Terrier biology business.industry Spaniel Allergens Antigens Plant biology.organism_classification Breed Confidence interval Dermatitis Seborrheic Hormones Cocker spaniel Labrador Retriever Female Analysis of variance business Hair |
| Zdroj: | Allergy. 60(8) |
| ISSN: | 0105-4538 |
| Popis: | Background: The clinical importance of dog allergy is well known, but it is unknown if all types of dogs represent the same risk for allergic patients. The purpose of this work was to evaluate among 288 healthy dogs if the levels of Can f 1 on fur vary between breeds (German Shepherd, Pyrenean Shepherd, Poodle, Cocker spaniel, Spaniel, Griffon, Labrador retriever and Yorkshire terrier), gender, hormonal status, hair length, and according to the presence of seborrhea. Methods: Each dog was shaved in a limited area and Can f 1 concentrations were measured in μg/g fur by ELISA. The results (geometric mean values and 95% confidence intervals) were analyzed using analysis of variance and with nonparametric tests. Results: A wide variability in Can f 1 levels was found between dog breeds, from Labradors [1.99 (0.03–129.91)] to Yorkshires [16.72 (3.67–76.16)] and Poodles [17.04 (2.79–103.94)] but only the Labrador levels were significantly different from each other breed. Males produced more Can f 1 than females, 11.75 (1.27–108.40) vs 8.89 (0.91–86.39). No difference was found according to hair length or hormonal status. The seborrheic status highly (P = 0.0019) influenced the presence of Can f 1 on hair: 16.66 (1.59–173.96) vs 9.40 (1.03–85.70). Conclusion: Breeds (Labrador retriever), sex and seborrhea seem to influence the levels of Can f 1 on fur. |
| Databáze: | OpenAIRE |
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