Audiovestibular sequelae of congenital cytomegalovirus infection in 3 children presumably representing 3 symptomatically different types of delayed endolymphatic hydrops

Autor: P.L.M. Huygen, R.J.C. Admiraal
Rok vydání: 1996
Předmět:
Male
medicine.medical_specialty
Adolescent
Hearing loss
Hearing Loss
Sensorineural
Congenital cytomegalovirus infection
Deafness
Audiology
Hearing Loss
Bilateral
Congenital cmv infection
Vertigo
Evoked Potentials
Auditory
Brain Stem
Saccades
otorhinolaryngologic diseases
medicine
Humans
Endolymphatic Hydrops
Endolymphatic hydrops
Child
Hearing Disorders
Nystagmus
Optokinetic
Vestibular system
Vestibular areflexia
Reflex
Abnormal
biology
business.industry
Infant
Auditory Threshold
General Medicine
Hearing Loss
Sudden
medicine.disease
biology.organism_classification
Pursuit
Smooth
Reflex
Acoustic
Vestibular Diseases
Otorhinolaryngology
Child
Preschool
Cytomegalovirus Infections
Pediatrics
Perinatology and Child Health
Female
sense organs
Differential diagnosis
medicine.symptom
business
Follow-Up Studies
Zdroj: International Journal of Pediatric Otorhinolaryngology. 35:143-154
ISSN: 0165-5876
Popis: Three cases of congenital cytomegalovirus (CMV) infection with long-term audiovestibular sequelae are presented. Case 1 had no hearing in one ear and severe progressive hearing loss in the other ear; he showed vestibular symptoms at the age of 4.5 years. Case 2 had severe but stationary hearing loss in one ear and showed hearing impairment symptoms in the other ear at 9-13 years of age. Case 3 did not have hearing impairment symptoms, or vestibular symptoms, but was found to have severe progressive hearing loss from the age of 15 months onwards, which led to profound deafness at the age of 2 years and vestibular areflexia at or before the age of 4 years. These cases may represent 3 symptomatically different types of delayed endolabyrinthine hydrops. Type 1 (ipsilateral hydrops) incorporates vestibular symptoms only because of a lack of hearing in the offending labyrinth. Type 2 (contralateral hydrops) incorporates hearing impairment symptoms only because of a lack of vestibular function on both sides and type 3 does not incorporate hearing impairment symptoms or vestibular symptoms (other than those relating to a complete lack of function). Given the present findings, those described by Weiss and Ronis (Trans. Pa. Acad. Opthalmol. Otolaryngol., 30 (1977) 52-54) in one case and other reported findings relating to histopathological or imaging methods in somewhat similar cases, it seems appropriate to include congenital CMV infection in the differential diagnosis of delayed endolymphatic hydrops.
Databáze: OpenAIRE
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