Delirium is independently associated with early mortality in elderly patients starting hemodialysis
| Autor: | Emi Sakamoto, Manami Tada, Yohei Arai, Shingo Shioji, Daisuke Katagiri, Minami Suzuki, Isao Kondo, Hiroyuki Tanaka, Fumihiko Hinoshita |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Physiology medicine.medical_treatment 030232 urology & nephrology Kaplan-Meier Estimate 030204 cardiovascular system & hematology behavioral disciplines and activities End stage renal disease 03 medical and health sciences 0302 clinical medicine Japan Renal Dialysis Physiology (medical) Internal medicine mental disorders medicine Humans Cognitive Dysfunction Dialysis Aged Proportional Hazards Models Retrospective Studies Aged 80 and over business.industry Hazard ratio Delirium Retrospective cohort study Confidence interval nervous system diseases Hospitalization Nephrology Cohort Kidney Failure Chronic Female Steroids Hemodialysis medicine.symptom business |
| Zdroj: | Clinical and Experimental Nephrology. 24:1077-1083 |
| ISSN: | 1437-7799 1342-1751 |
| Popis: | Delirium is an independent predictor of death in patients undergoing dialysis for end-stage renal disease (ESRD). However, it is unknown whether delirium during hospitalization at the start of hemodialysis (HD) in elderly populations is associated with early mortality. We conducted a retrospective cohort study to investigate the association between delirium and early mortality in the elderly after starting HD. The cohort consisted of patients ≥ 75 years who started dialysis for ESRD at the National Center for Global Health and Medicine from 2010 to 2017 and at Yokosuka Kyosai Hospital from 2007 to 2011. Delirium was defined as patients who showed new symptoms of transient confused thinking and reduced awareness of their environment and were prescribed antipsychotic medications. The primary outcome was death within 1 year. Data were analyzed using Cox proportional hazard models with adjustments for baseline characteristics. A multinomial logistic regression was used to identify the determinants of patients developing delirium. We enrolled 259 patients (males, 60%); 33 patients were diagnosed with delirium. The primary outcome was observed in 19 patients with delirium (58%) and 24 patients without delirium (11%) (p |
| Databáze: | OpenAIRE |
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