Association Between Albumin-Bilirubin Score at Admission and In-Hospital Mortality in Patients with Acute Heart Failure
| Autor: | Atsushi Ikeda, Shunsuke Komatsu, Takayuki Kawata, Hiroshi Masuda |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Vital signs Liver disease Japan Internal medicine medicine Humans Hospital Mortality Serum Albumin Aged Retrospective Studies Aged 80 and over Heart Failure Framingham Risk Score business.industry Mortality rate Bilirubin General Medicine Odds ratio medicine.disease Confidence interval Echocardiography Heart failure Female Liver function Cardiology and Cardiovascular Medicine business |
| Zdroj: | International Heart Journal. 62:829-836 |
| ISSN: | 1349-3299 1349-2365 |
| DOI: | 10.1536/ihj.21-080 |
| Popis: | Liver dysfunction is one of the most recognized complications in patients with acute heart failure (HF) and therefore a liver function score may be useful for risk-stratification in those patients. Recently, the albumin-bilirubin (ALBI) score was developed as a new model to assess liver function in liver disease. We explored the association between the ALBI score at admission and in-hospital mortality in patients with acute HF.We enrolled 262 patients (median age, 86 years, 137 males) who were admitted to our hospital for treatment of acute HF. The following data were recorded: vital signs, laboratory data including B-type natriuretic peptide (BNP) level, echocardiographic data at admission, demographic and clinical characteristics, and treatment and prognostic information. The Get With the Guidelines-Heart Failure (GWTG-HF) risk score was calculated as an established risk model for each patient. The primary outcome was all-cause in-hospital mortality.During hospitalization, 37 patients (14.1%) died. The in-hospital mortality rate was significantly higher in patients with ALBI scores > -2.25 compared with patients with ALBI scores ≤ -2.25 (21.1% versus 4.5%, respectively; P = 0.0001). Multivariate analysis revealed that the GWTG-HF score (odds ratio [OR] 1.16, 95% confidence interval [CI] 1.08-1.25, P < 0.0001), BNP level (OR 1.0007, 95% CI 1.0003-1.001, P = 0.0003) and ALBI score (OR 6.0, 95% CI 1.8-19.6, P = 0.0017) were independently associated with in-hospital mortality.Our results indicated that the ALBI score was independently associated with in-hospital mortality in patients hospitalized for acute HF. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|