Is there a correlation between skull base flexure and palatal anomalies in patients with 22q11 deletion syndrome and velopharyngeal dysfunction?
| Autor: | Ariela Nachmani, Doron Gothelf, Muhamed Masalha, Ben I. Nageris, Eias Kassem, Firas Kassem |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male 22q11 Deletion Syndrome Velopharyngeal Insufficiency Adolescent Cephalometry Correlation Young Adult Medicine Humans In patient Child Retrospective Studies Orthodontics Skull Base business.industry Craniometry Cleft Palate Skull medicine.anatomical_structure Otorhinolaryngology Submucous cleft palate Child Preschool Palatal anomalies Surgery Female Velopharyngeal dysfunction Oral Surgery business |
| Zdroj: | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 49(9) |
| ISSN: | 1878-4119 |
| Popis: | The study aimed at assessing the relationship between skull base morphology, represented by skull base and nasopharyngeal angles, and palatal anatomy among patients with 22q11DS and velopharyngeal dysfunction. Retrospective analysis of patients with 22q11DS and velopharyngeal dysfunction. Age, sex, severity of velopharyngeal dysfunction, type of cleft (overt cleft palate, submucous cleft palate, occult submucous cleft palate, or no-CP, and cephalometric skull base angles were reviewed. Correlations between type of palatal anomaly and the angles were assessed. Among 132 patients, 71 were male (53.8%) and 61 were female (46.2%), ages 3.3–40.0 years (mean 8.3 ± 6.10). No difference in the mean cranial-base angle (P = 0.353) or in the distribution of the three types of cranial base angle sizes was found among the palatal anomaly groups (P = 0.137). More men had normal cranial base angles and more women had acute angulation (P = 0.008). A positive correlation was found between the skull base and nasopharyngeal angles (P = 0.001, r = −0.590). No direct correlation was found between cranial base morphology and palatal anomalies in patients with 22q11DS, and velopharyngeal dysfunction. This is probably because skull base and palate morphology contribute independently to velopharyngeal dysfunction. |
| Databáze: | OpenAIRE |
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