Biosynthesis of acteoside in cultured cells of Olea europaea

Autor:	Yutaka Orihara, Hiroshi Saimaru
Rok vydání:	2009
Předmět:	chemistry.chemical_classification biology Plant Extracts Salidroside Glycoside Phenylalanine Phenylethanoid biology.organism_classification chemistry.chemical_compound Verbascoside Glucosides Phenols chemistry Biochemistry Biosynthesis Olea Molecular Medicine Hydroxytyrosol Cells Cultured
Zdroj:	Journal of Natural Medicines. 64:139-145
ISSN:	1861-0293 1340-3443
DOI:	10.1007/s11418-009-0383-z
Popis:	Five phenylethanoid glycosides (acteoside, isoacteoside, beta-oxoacteoside, beta-hydroxyacteoside, and salidroside) were isolated from a cell suspension culture of Olea europaea. We examined the biosynthesis of acteoside in olive cell cultures by using feeding experiments with stable isotope labeled precursors. The hydroxytyrosol moiety of acteoside is biosynthesized from tyrosine through dopamine, whereas the caffeoyl moiety of acteoside is biosynthesized from phenylalanine via a cinnamate pathway. Dopamine is incorporated into acteoside through oxidation to the corresponding aldehyde, reduction to the alcohol, and then beta-glycosylation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d984c091a2bdad0c51e25d4c7a565d0e https://doi.org/10.1007/s11418-009-0383-z Zobrazit plný text záznamu Full text from SpringerLink