Enhanced Recovery After Surgery program with dexamethasone administration for major head and neck surgery with free tissue transfer reconstruction: initial institutional experience

Autor:	Keitaro Fujii, Kayo Yamaguchi, Sinkichi Morita, Yukinori Asada, Ko Matsumoto, Kazuhiro Kishimoto, Satoshi Saijo, Kazuto Matsuura, Koreyuki Kurosawa, Takayuki Imai, Takahiro Goto, Naoko Satake, Jiro Aoi
Rok vydání:	2018
Předmět:	Male medicine.medical_specialty Free Tissue Flaps Dexamethasone Perioperative Care 03 medical and health sciences Postoperative Complications 0302 clinical medicine medicine Humans 030223 otorhinolaryngology Glucocorticoids Enhanced recovery after surgery Aged Retrospective Studies Inflammation business.industry fungi Hemodynamics food and beverages Postoperative complication Retrospective cohort study General Medicine Length of Stay Middle Aged Surgery Tissue transfer Otorhinolaryngology Head and Neck Neoplasms 030220 oncology & carcinogenesis Tissue Transplantation Perioperative care Head and neck surgery Female business Glucocorticoid medicine.drug
Zdroj:	Acta Oto-Laryngologica. 138:664-669
ISSN:	1651-2251 0001-6489
DOI:	10.1080/00016489.2018.1429651
Popis:	Enhanced Recovery After Surgery (ERAS) protocols promote recovery after various invasive surgeries. Likewise, preoperative glucocorticoid administration can reduce complications after some surgeries. However, the effects of ERAS protocols and glucocorticoid administration in patients undergoing major surgery for head and neck cancer have not been well described. The aim of this study was to evaluate the effect of an ERAS protocol with preoperative glucocorticoid administration in major surgery for head and neck cancer.This retrospective study included 28 patients who underwent major head and neck surgery with free tissue transfer reconstruction at our institution from September 2016 to May 2017, after implementation of an ERAS protocol with preoperative glucocorticoid administration. Outcomes in that group were compared with those in a control group that underwent surgery from January 2015 to September 2016, before implementation of the protocol.Analysis revealed significantly less body weight fluctuation, lower C-reactive protein levels, higher albumin levels, and lower body temperature in the ERAS group than in the control group postoperatively.Patients undergoing major surgery for head and neck cancer who were treated with the ERAS protocol and preoperative glucocorticoid administration had evidence of better hemodynamic stability and less inflammatory response than control patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d984b54a97337b9d0f2eed5dd7f5c931 https://doi.org/10.1080/00016489.2018.1429651 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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