Extracellular amoebal-vesicles: potential transmission vehicles for respiratory viruses
| Autor: | Nicholas J. Ashbolt, Rafik Dey, Melanie A. Folkins |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Adult Water microbiology viruses Respiratory Syncytial Virus Infections Biology Virus Replication Brief Communication Applied Microbiology and Biotechnology Microbiology Models Biological Virus Microbial ecology 03 medical and health sciences Extracellular Vesicles Immunocompromised Host 0302 clinical medicine Extracellular Humans 030212 general & internal medicine Respiratory system Amoeba Child Respiratory tract infections Transmission (medicine) Vesicle QR100-130 030104 developmental biology Respiratory Syncytial Virus Human Biofilms Pathogens Biotechnology HeLa Cells |
| Zdroj: | NPJ Biofilms and Microbiomes npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-5 (2021) |
| ISSN: | 2055-5008 |
| Popis: | Human respiratory syncytial virus (RSV) is a major cause of acute respiratory tract infections in children and immunocompromised adults worldwide. Here we report that amoebae-release respirable-sized vesicles containing high concentrations of infectious RSV that persisted for the duration of the experiment. Given the ubiquity of amoebae in moist environments, our results suggest that extracellular amoebal-vesicles could contribute to the environmental persistence of respiratory viruses, including potential resistance to disinfection processes and thereby offering novel pathways for viral dissemination and transmission. |
| Databáze: | OpenAIRE |
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