A study of the effectiveness of botulinum toxin type A (Dysport) in the management of muscle spasticity
| Autor: | Yuriko Watanabe, A. M. O. Bakheit, D L McLellan |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Disease Physical medicine and rehabilitation medicine Humans Neuromuscular Agents Spasticity Botulinum Toxins Type A Child Adverse effect Retrospective Studies business.industry Rehabilitation Retrospective cohort study Sensory loss Middle Aged Botulinum toxin Treatment Outcome Muscle Spasticity Child Preschool Physical therapy Female medicine.symptom business medicine.drug Botulinum toxin type |
| Zdroj: | Disability and Rehabilitation. 20:62-65 |
| ISSN: | 1464-5165 0963-8288 |
| DOI: | 10.3109/09638289809166055 |
| Popis: | Severe muscle spasticity is common in patients with neurological disease. It is often associated with pain and distressing spasms, and frequently leads to functional motor disability. Antispasticity drugs usually result in systemic adverse effects, and peripheral nerve blocks have some disadvantages such as sensory loss and painful dysaesthesiae. In recent years botulinum toxin type A (BT/A) has been advocated for the treatment of muscle spasticity. We studied, using a functional assessment scale, the effects of BT/A on the patients' symptoms and the functional disability due to spasticity in five children and eight adults who were referred for treatment. In 10 patients the treatment goals were achieved, and children generally had a better and more sustained response than adults. There were no adverse effects reported. The present study suggests that BT/A is safe and effective in improving the motor functional disability which is often associated with severe localized muscle spasticity. |
| Databáze: | OpenAIRE |
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