Cognitive Performance after Lacunar Stroke Correlates with Leukoaraiosis Severity
| Autor: | Mario F. Mendez, Aaron McMurtray, Janelle M. Haider, Eliot A. Licht, Alex Liao |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Brain Infarction Male medicine.medical_specialty Lacunar stroke Neuropsychological Tests Severity of Illness Index Cognition Physical medicine and rehabilitation Risk Factors Severity of illness medicine Humans cardiovascular diseases Effects of sleep deprivation on cognitive performance Vascular dementia Stroke Aged Aged 80 and over medicine.diagnostic_test business.industry Leukoaraiosis Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging nervous system diseases body regions Neurology Female Neurology (clinical) Cognition Disorders Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cerebrovascular Diseases. 24:271-276 |
| ISSN: | 1421-9786 1015-9770 |
| DOI: | 10.1159/000105679 |
| Popis: | Background: This study investigates the effect of leukoaraiosis on patients presenting with cognitive impairment after lacunar stroke. Methods: Fourty-six patients with cognitive impairment and newly discovered lacunar stroke detected by brain magnetic resonance imaging underwent neuropsychological testing. Results: Patients with both lacunar infarct and leukoaraiosis performed less well on cognitive measures, compared to those with lacunar infarcts alone. Additionally, leukoaraiosis severity inversely correlated with cognitive performance. Conclusions: In patients with lacunar stroke, presence of leukoaraiosis is associated with worse performance in multiple cognitive domains. These findings suggest lacunar infarcts plus leukoaraiosis is a common etiology for vascular dementia. |
| Databáze: | OpenAIRE |
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