The effect of the non-steroidal anti-inflammatory drug choline magnesium trisalicylate on gastric mucosal cell exfoliation
| Autor: | GP Crean, J. Hearns, KG Mitchell |
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| Rok vydání: | 1984 |
| Předmět: |
Drug
Adult Male medicine.medical_specialty congenital hereditary and neonatal diseases and abnormalities Choline Magnesium Trisalicylate Nausea media_common.quotation_subject Placebo Exfoliation (cosmetology) Gastroenterology Choline chemistry.chemical_compound Random Allocation Internal medicine medicine Humans Pharmacology (medical) media_common Pharmacology Aspirin Stomach Salicylates Surgery nervous system diseases medicine.anatomical_structure chemistry Gastric Mucosa Female medicine.symptom Salicylic Acid Salicylic acid medicine.drug Research Article |
| Zdroj: | British journal of clinical pharmacology. 17(1) |
| ISSN: | 0306-5251 |
| Popis: | Gastric mucosal cell exfoliation was measured in 10 normal subjects taking choline magnesium trisalicylate (CMT), aspirin and placebo. Both drugs resulted in significantly elevated rates of exfoliation although the serum salicylate levels achieved with aspirin were lower than those achieved by CMT. Side-effects of tinnitus, nausea and increased faecal blood loss were more common while subjects were taking CMT. |
| Databáze: | OpenAIRE |
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