Contrast Administration in Pediatric Cardiac Catheterization: Dose and Adverse Events
| Autor: | Kimberlee Gauvreau, James E. Lock, Audrey C. Marshall, Lisa Bergersen, Selvi Senthilnathan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Cardiac Catheterization Time Factors Adolescent media_common.quotation_subject medicine.medical_treatment Contrast Media Coronary Angiography Risk Assessment Article Nephropathy Risk Factors Triiodobenzoic Acids medicine Contrast (vision) Humans Radiology Nuclear Medicine and imaging Adverse effect Child media_common Cardiac catheterization Retrospective Studies Dose-Response Relationship Drug business.industry Medical record Incidence (epidemiology) Body Weight Age Factors Infant Retrospective cohort study General Medicine medicine.disease Surgery Quartile Anesthesia Child Preschool Kidney Diseases Nervous System Diseases Cardiology and Cardiovascular Medicine business |
| Zdroj: | Catheter Cardiovasc Interv |
| Popis: | BACKGROUND: In pediatrics, contrast-related AE such as allergic reactions, seizures, and nephropathy have been reported to occur after cardiac catheterization, but their incidence remains unknown. OBJECTIVE: We sought to report adverse event (AE) rates attributed to contrast administration in a pediatric cardiac catheterization lab and identify characteristics related to higher doses. METHODS: A single institution prospective cardiac catheterization AE database identified AE in children 2 h (67% vs. 28%), all P < 0.001. Only 2 of 2,321 cases (0.09%, 95% CI 0.01–0.31%) had AE possibly related to contrast. These events were an acute neurological change and transient nephropathy. In 50 cases receiving the most contrast, no AE were attributed to contrast. CONCLUSION: A large volume pediatric cardiac catheterization lab administered ≥ 6 cm3/kg of contrast in a quarter of cases; however, AE related to contrast exposure were exceedingly rare. |
| Databáze: | OpenAIRE |
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